Attenuated Actinobacillus pleuropneumoniae double-deletion mutant S-8∆clpP/apxIIC confers protection against homologous or heterologous strain challenge

BACKGROUND: Actinobacillus pleuropneumoniae is the etiological agent of porcine pleuropneumonia, which leads to large economic losses to the swine industry worldwide. In this study, S-8△clpP△apxIIC, a double-deletion mutant of A. pleuropneumoniae was constructed, and its safety and protective effica...

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Udgivet i:BMC Vet Res
Main Authors: Xie, Fang, Li, Gang, Zhou, Long, Zhang, Yanhe, Cui, Ning, Liu, Siguo, Wang, Chunlai
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2017
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5219649/
https://ncbi.nlm.nih.gov/pubmed/28061786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12917-016-0928-9
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