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When your cap matters: structural insights into self vs non-self recognition of 5′ RNA by immunomodulatory host proteins

Cytosolic recognition of viral RNA is important for host innate immune responses. Differential recognition of self vs non-self RNA is a considerable challenge as the inability to differentiate may trigger aberrant immune responses. Recent work identified the composition of the RNA 5′, including the...

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Vydáno v:Curr Opin Struct Biol
Hlavní autoři: Leung, Daisy W, Amarasinghe, Gaya K
Médium: Artigo
Jazyk:Inglês
Vydáno: Published by Elsevier Ltd. 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5218996/
https://ncbi.nlm.nih.gov/pubmed/26916433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sbi.2016.02.001
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