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When your cap matters: structural insights into self vs non-self recognition of 5′ RNA by immunomodulatory host proteins

Cytosolic recognition of viral RNA is important for host innate immune responses. Differential recognition of self vs non-self RNA is a considerable challenge as the inability to differentiate may trigger aberrant immune responses. Recent work identified the composition of the RNA 5′, including the...

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Publicat a:Curr Opin Struct Biol
Autors principals: Leung, Daisy W, Amarasinghe, Gaya K
Format: Artigo
Idioma:Inglês
Publicat: Published by Elsevier Ltd. 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5218996/
https://ncbi.nlm.nih.gov/pubmed/26916433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sbi.2016.02.001
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