Rifalazil Treats and Prevents Relapse of Clostridium difficile-Associated Diarrhea in Hamsters

Although vancomycin and metronidazole effectively treat Clostridium difficile-associated diarrhea and colitis (CDAD), their use is associated with a high incidence of relapsing C. difficile infection. Rifalazil is a new benzoxazinorifamycin that possesses activity against Mycobacterium tuberculosis...

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Bibliographic Details
Main Authors: Anton, Pauline M., O'Brien, Michael, Kokkotou, Efi, Eisenstein, Barry, Michaelis, Arthur, Rothstein, David, Paraschos, Sophia, Kelly, Ciáran P., Pothoulakis, Charalabos
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2004
Subjects:
Experimental Therapeutics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC521872/
https://ncbi.nlm.nih.gov/pubmed/15388461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.10.3975-3979.2004
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