Farnesoid X Receptor Activation Attenuates Intestinal Ischemia Reperfusion Injury in Rats

INTRODUCTION: The farnesoid X receptor (FXR) is abundantly expressed in the ileum, where it exerts an enteroprotective role as a key regulator of intestinal innate immunity and homeostasis, as shown in pre-clinical models of inflammatory bowel disease. Since intestinal ischemia reperfusion injury (I...

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Gepubliceerd in:PLoS One
Hoofdauteurs: Ceulemans, Laurens J., Verbeke, Len, Decuypere, Jean-Paul, Farré, Ricard, De Hertogh, Gert, Lenaerts, Kaatje, Jochmans, Ina, Monbaliu, Diethard, Nevens, Frederik, Tack, Jan, Laleman, Wim, Pirenne, Jacques
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2017
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5218501/
https://ncbi.nlm.nih.gov/pubmed/28060943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0169331
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