Age-Associated ALU Element Instability in White Blood Cells Is Linked to Lower Survival in Elderly Adults: A Preliminary Cohort Study

BACKGROUND: ALU element instability could contribute to gene function variance in aging, and may partly explain variation in human lifespan. OBJECTIVE: To assess the role of ALU element instability in human aging and the potential efficacy of ALU element content as a marker of biological aging and s...

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Publicat a:PLoS One
Autors principals: Morgan, R. Garrett, Venturelli, Massimo, Gross, Cole, Tarperi, Cantor, Schena, Federico, Reggiani, Carlo, Naro, Fabio, Pedrinolla, Anna, Monaco, Lucia, Richardson, Russell S., Donato, Anthony J.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2017
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Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5218400/
https://ncbi.nlm.nih.gov/pubmed/28060910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0169628
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