Lentivirus-Mediated RNA Interference of DC-SIGN Expression Inhibits Human Immunodeficiency Virus Transmission from Dendritic Cells to T Cells

In the early events of human immunodeficiency virus type 1 (HIV-1) infection, immature dendritic cells (DCs) expressing the DC-specific intercellular adhesion molecule 3-grabbing nonintegrin (DC-SIGN) receptor capture small amounts of HIV-1 on mucosal surfaces and spread viral infection to CD4(+) T...

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Autori principali: Arrighi, Jean-François, Pion, Marjorie, Wiznerowicz, Maciej, Geijtenbeek, Teunis B., Garcia, Eduardo, Abraham, Shahnaz, Leuba, Florence, Dutoit, Valérie, Ducrey-Rundquist, Odile, van Kooyk, Yvette, Trono, Didier, Piguet, Vincent
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2004
Soggetti:
Virus-Cell Interactions
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC521813/
https://ncbi.nlm.nih.gov/pubmed/15452205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.20.10848-10855.2004
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