Multi-omics Analysis of Serum Samples Demonstrates Reprogramming of Organ Functions Via Systemic Calcium Mobilization and Platelet Activation in Metastatic Melanoma

Pathophysiologies of cancer-associated syndromes such as cachexia are poorly understood and no routine biomarkers have been established, yet. Using shotgun proteomics, known marker molecules including PMEL, CRP, SAA, and CSPG4 were found deregulated in patients with metastatic melanoma. Targeted ana...

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Détails bibliographiques
Publié dans:Mol Cell Proteomics
Auteurs principaux: Muqaku, Besnik, Eisinger, Martin, Meier, Samuel M., Tahir, Ammar, Pukrop, Tobias, Haferkamp, Sebastian, Slany, Astrid, Reichle, Albrecht, Gerner, Christopher
Format: Artigo
Langue:Inglês
Publié: The American Society for Biochemistry and Molecular Biology 2017
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5217785/
https://ncbi.nlm.nih.gov/pubmed/27879288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M116.063313
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