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The use of novel selectivity metrics in kinase research
BACKGROUND: Compound selectivity is an important issue when developing a new drug. In many instances, a lack of selectivity can translate to increased toxicity. Protein kinases are particularly concerned with this issue because they share high sequence and structural similarity. However, selectivity...
Gorde:
| Argitaratua izan da: | BMC Bioinformatics |
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| Egile Nagusiak: | , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
BioMed Central
2017
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5217660/ https://ncbi.nlm.nih.gov/pubmed/28056771 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-016-1413-y |
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