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Epiregulin as a therapeutic target in non-small-cell lung cancer
Epiregulin (EREG) belongs to the ErbB family of ligands. EREG binds to EGFR and ErbB4 receptor and stimulates homodimers of EGFR and ErbB4 in addition to all possible heterodimeric ErbB complexes, resulting in the activation of downstream signaling pathways. EREG is overexpressed in various human ca...
Gespeichert in:
| Veröffentlicht in: | Lung Cancer (Auckl) |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Dove Medical Press
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5217521/ https://ncbi.nlm.nih.gov/pubmed/28210154 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/LCTT.S60427 |
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