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Profile of bavituximab and its potential in the treatment of non-small-cell lung cancer

Bavituximab is a an unconjugated, chimeric immunoglobulin G1 (IgG1) monoclonal antibody directed against the phosphatidylserine (PS) expressed on tumor endothelium, with a specific mechanism of action. PS is an anionic membrane phospholipid, physiologically restricted to the internal membrane leafle...

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Detalhes bibliográficos
Publicado no:Lung Cancer (Auckl)
Main Authors: Stasi, Irene, Cappuzzo, Federico
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5217514/
https://ncbi.nlm.nih.gov/pubmed/28210141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/LCTT.S37981
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