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Profile of bavituximab and its potential in the treatment of non-small-cell lung cancer
Bavituximab is a an unconjugated, chimeric immunoglobulin G1 (IgG1) monoclonal antibody directed against the phosphatidylserine (PS) expressed on tumor endothelium, with a specific mechanism of action. PS is an anionic membrane phospholipid, physiologically restricted to the internal membrane leafle...
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| Опубликовано в: : | Lung Cancer (Auckl) |
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| Главные авторы: | , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Dove Medical Press
2014
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5217514/ https://ncbi.nlm.nih.gov/pubmed/28210141 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/LCTT.S37981 |
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