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Gastroesophageal junction adenocarcinoma displays abnormalities in homologous recombination and nucleotide excision repair

OBJECTIVE: Esophageal adenocarcinoma (EAC) continues to be a disease associated with high mortality. Among the factors leading to poor outcomes are innate resistance to currently available therapies, advanced stage at diagnosis, and complex biology. Platinum and ionizing radiation form the backbone...

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Podrobná bibliografie
Vydáno v:Lung Cancer (Auckl)
Hlavní autoři: Dewalt, Robin I, Kesler, Kenneth A, Hammoud, Zane T, Baldridge, LeeAnn, Hattab, Eyas M, Jalal, Shadia I
Médium: Artigo
Jazyk:Inglês
Vydáno: Dove Medical Press 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5217507/
https://ncbi.nlm.nih.gov/pubmed/28210138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/LCTT.S57594
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