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Cigarette smoke destabilizes NLRP3 protein by promoting its ubiquitination
BACKGROUND: Cigarette smoke suppresses innate immunity, making smokers more susceptible to infection. The NLRP3 inflammasome is a multi-protein complex that releases interleukin (IL) -1β and IL -18. These cytokines are critical for a timely host response to pathogens. Whether cigarette smoke affects...
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| Publicado no: | Respir Res |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5217194/ https://ncbi.nlm.nih.gov/pubmed/28056996 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-016-0485-6 |
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