EphrinA4 plays a critical role in α4 and αL mediated survival of human CLL cells during extravasation

A role of endothelial cells in the survival of CLL cells during extravasation is presently unknown. Herein we show that CLL cells but not normal B cells can receive apoptotic signals through physical contact with TNF-α activated endothelium impairing survival in transendothelial migration (TEM) assa...

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Pubblicato in:Oncotarget
Autori principali: Flores, Miguel A., Fortea, Paula, Trinidad, Eva M., García, Dolores, Soler, Gloria, Ortuño, Francisco J., Zapata, Agustín G., Alonso, Luis M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2016
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5217033/
https://ncbi.nlm.nih.gov/pubmed/27374180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10311
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