miR-200b is a key regulator of tumor progression and metabolism targeting lactate dehydrogenase A in human malignant glioma

Lactate dehydrogenase A (LDHA) is involved in various cancers. In this study, we investigated the expression and function of LDHA in glioma. We found that LDHA was up-regulated in glioma samples. Furthermore, we found that overexpression of LDHA promoted proliferation, invasion and glycolysis in gli...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Hu, Su, Jiang, Qian, Luo, Dongdong, Zhao, Lei, Fu, Xin, Chen, Yuqin, Song, Xue, Li, Lihua, Zhao, Hailin, He, Yingfang, Peng, Biao
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5217028/
https://ncbi.nlm.nih.gov/pubmed/27374173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10301
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