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MicroRNA-106b~25 cluster is upregulated in relapsed MLL-rearranged pediatric acute myeloid leukemia

The most important reason for therapy failure in pediatric acute myeloid leukemia (AML) is relapse. In order to identify miRNAs that contribute to the clonal evolution towards relapse in pediatric AML, miRNA expression profiling of 127 de novo pediatric AML cases were used. In the diagnostic phase,...

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Veröffentlicht in:Oncotarget
Hauptverfasser: Verboon, Lonneke J., Obulkasim, Askar, de Rooij, Jasmijn D.E., Katsman, Jenny E., Sonneveld, Edwin, Baruchel, André, Trka, Jan, Reinhardt, Dirk, Pieters, Rob, Cloos, Jacqueline, Kaspers, Gertjan J.L., Klusmann, Jan-Henning, Zwaan, Christian Michel, Fornerod, Maarten, van den Heuvel-Eibrink, Marry M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2016
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5217027/
https://ncbi.nlm.nih.gov/pubmed/27351222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10270
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