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Downregulation of HP1α suppresses proliferation of cholangiocarcinoma by restoring SFRP1 expression
Heterochromatin protein 1α (HP1α) is a gene that mediates chromatin conformation, gene silencing and cancer progression. However, little is known regarding the impact of HP1α in the pathogenesis of cholangiocarcinoma (CCA). In the present study, we demonstrate that HP1α is significantly upregulated...
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| Veröffentlicht in: | Oncotarget |
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| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Impact Journals LLC
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5217004/ https://ncbi.nlm.nih.gov/pubmed/27385214 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10371 |
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