Safety assessment of inhaled xylitol in mice and healthy volunteers

BACKGROUND: Xylitol is a 5-carbon sugar that can lower the airway surface salt concentration, thus enhancing innate immunity. We tested the safety and tolerability of aerosolized iso-osmotic xylitol in mice and human volunteers. METHODS: This was a prospective cohort study of C57Bl/6 mice in an anim...

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Autori principali: Durairaj, Lakshmi, Launspach, Janice, Watt, Janet L, Businga, Thomas R, Kline, Joel N, Thorne, Peter S, Zabner, Joseph
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2004
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC521689/
https://ncbi.nlm.nih.gov/pubmed/15377394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-5-13
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