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Endophenotypes, Epigenetics, Polygenicity and More: Irv Gottesman’s Dynamic Legacy

First, we describe the hallmark contributions of Irv Gottesman’s pioneering scholarship for schizophrenia research including concepts of polygenicity, gene × environment interactions, epigenetics and the endophenotype concept. Gottesman and colleagues’ twin studies showed that genes, not social fact...

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Detalhes bibliográficos
Publicado no:Schizophr Bull
Main Authors: Braff, David L., Tamminga, Carol A.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5216869/
https://ncbi.nlm.nih.gov/pubmed/27872267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/schbul/sbw157
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