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Strengths and weaknesses of EST-based prediction of tissue-specific alternative splicing

BACKGROUND: Alternative splicing contributes significantly to the complexity of the human transcriptome and proteome. Computational prediction of alternative splice isoforms are usually based on EST sequences that also allow to approximate the expression pattern of the related transcripts. However,...

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Autores principales: Gupta, Shobhit, Zink, Dorothea, Korn, Bernhard, Vingron, Martin, Haas, Stefan A
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2004
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC521684/
https://ncbi.nlm.nih.gov/pubmed/15453915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-5-72
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