Delta-9-tetrahydrocannabinol protects against MPP(+) toxicity in SH-SY5Y cells by restoring proteins involved in mitochondrial biogenesis

Proliferator-activated receptor γ (PPARγ) activation can result in transcription of proteins involved in oxidative stress defence and mitochondrial biogenesis which could rescue mitochondrial dysfunction in Parkinson's disease (PD). The PPARγ agonist pioglitazone is protective in models of PD;...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Zeissler, Marie-Louise, Eastwood, Jordan, McCorry, Kieran, Hanemann, C. Oliver, Zajicek, John P., Carroll, Camille B.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5216821/
https://ncbi.nlm.nih.gov/pubmed/27366949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10314
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