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Overexpression of Cathepsin L is associated with chemoresistance and invasion of epithelial ovarian cancer

Paclitaxel is recommended as a first-line chemotherapeutic agent against, ovarian cancer, however, the development of chemoresistance is a major obstacle in patients with aggressive ovarian cancer and results in recurrence after conventional therapy. The key molecule or mechanism associated with pac...

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Pubblicato in:Oncotarget
Autori principali: Sui, Hongying, Shi, Caixia, Yan, Zhipeng, Wu, Mei
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5216776/
https://ncbi.nlm.nih.gov/pubmed/27351223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10276
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