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Thermodynamic, kinetic and structural basis for recognition and repair of abasic sites in DNA by apurinic/apyrimidinic endonuclease from human placenta

X-ray analysis of enzyme–DNA interactions is very informative in revealing molecular contacts, but provides neither quantitative estimates of the relative importance of these contacts nor information on the relative contributions of specific and nonspecific interactions to the total affinity of enzy...

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Autori principali: Beloglazova, Natalia G., Kirpota, Oleg O., Starostin, Konstantin V., Ishchenko, Alexander A., Yamkovoy, Vitaly I., Zharkov, Dmitry O., Douglas, Kenneth T., Nevinsky, Georgy A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2004
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC521659/
https://ncbi.nlm.nih.gov/pubmed/15459284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh846
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