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Airway autoimmune responses in severe eosinophilic asthma following low-dose Mepolizumab therapy

BACKGROUND: Anti-interleukin (IL)-5 monoclonal antibodies as an eosinophil-depleting strategy is well established, with Mepolizumab being the first biologic approved as an adjunct treatment for severe eosinophilic asthma. CASE PRESENTATION: A 62-year old woman diagnosed with severe eosinophilic asth...

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Detalhes bibliográficos
Publicado no:Allergy Asthma Clin Immunol
Main Authors: Mukherjee, Manali, Lim, Hui Fang, Thomas, Sruthi, Miller, Douglas, Kjarsgaard, Melanie, Tan, Bruce, Sehmi, Roma, Khalidi, Nader, Nair, Parameswaran
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5216532/
https://ncbi.nlm.nih.gov/pubmed/28070196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13223-016-0174-5
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