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The Live Attenuated Cholera Vaccine CVD 103-HgR Primes Responses to the Toxin-Coregulated Pilus Antigen TcpA in Subjects Challenged with Wild-Type Vibrio cholerae

One potential advantage of live attenuated bacterial vaccines is the ability to stimulate responses to antigens which are only expressed during the course of infection. To determine whether the live attenuated cholera vaccine CVD 103-HgR (Vaxchora) results in antibody responses to the in vivo-induce...

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Détails bibliographiques
Publié dans:Clin Vaccine Immunol
Auteurs principaux: Mayo-Smith, Leslie M., Simon, Jakub K., Chen, Wilbur H., Haney, Douglas, Lock, Michael, Lyon, Caroline E., Calderwood, Stephen B., Kirkpatrick, Beth D., Cohen, Mitchell, Levine, Myron M., Gurwith, Marc, Harris, Jason B.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5216439/
https://ncbi.nlm.nih.gov/pubmed/27847368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00470-16
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