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A novel hybrid compound LLP2A-Ale both prevented and rescued the osteoporotic phenotype in a mouse model of glucocorticoid-induced osteoporosis

Prolonged glucocorticoid (GC) administration causes secondary osteoporosis (GIOP) and non-traumatic osteonecrosis. LLP2A-Ale is a novel bone seeking compound that recruits mesenchymal stem cells to the bone surface, stimulates bone formation, and increases bone mass. The purpose of this study was to...

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Detalhes bibliográficos
Publicado no:Calcif Tissue Int
Main Authors: Mohan, Geetha, Lay, Evan Yu-An, Berka, Haley, Ringwood, Lorna, Kot, Alexander, Chen, Haiyan, Yao, Wei, Lane, Nancy E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5215964/
https://ncbi.nlm.nih.gov/pubmed/27679514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00223-016-0195-6
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