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Soluble B and T Lymphocyte Attenuator Correlates to Disease Severity in Sepsis and High Levels Are Associated with an Increased Risk of Mortality

INTRODUCTION AND AIMS: B- and T-lymphocyte Attenuator (BTLA), Cytotoxic T-lymphocyte-associated protein 4 (CTLA-4) and Programmed Death 1 (PD-1) are co-inhibitory receptors that regulate T cell activation. In the present study of ICU-treated patients we measured plasma concentrations of their solubl...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Lange, Anna, Sundén-Cullberg, Jonas, Magnuson, Anders, Hultgren, Olof
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5215942/
https://ncbi.nlm.nih.gov/pubmed/28056053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0169176
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