Tbx5 Buffers Inherent Left/Right Asymmetry Ensuring Symmetric Forelimb Formation

The forelimbs and hindlimbs of vertebrates are bilaterally symmetric. The mechanisms that ensure symmetric limb formation are unknown but they can be disrupted in disease. In Holt-Oram Syndrome (HOS), caused by mutations in TBX5, affected individuals have left-biased upper/forelimb defects. We demon...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Gepubliceerd in:PLoS Genet
Hoofdauteurs: Sulaiman, Fatima A., Nishimoto, Satoko, Murphy, George R. F., Kucharska, Anna, Butterfield, Natalie C., Newbury-Ecob, Ruth, Logan, Malcolm P. O.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2016
Onderwerpen:
Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5215935/
https://ncbi.nlm.nih.gov/pubmed/27992425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006521
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items