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Role of diversifying selection and gene conversion in evolution of major histocompatibility complex loci.

Genes at the major histocompatibility complex (MHC) in mammals are known to have exceptionally high polymorphism and linkage disequilibrium. In addition, these genes form highly complicated gene families that have evolved through gene conversion and unequal crossing-over. It has been shown recently...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteur principal: Ohta, T
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 1991
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC52159/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1862096/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.15.6716
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