Keratin-associated protein 5-5 controls cytoskeletal function and cancer cell vascular invasion

Cancer cell vascular invasion is a crucial step in the malignant progression towards metastasis. Here we used a genome-wide RNAi screen with E0771 mammary cancer cells to uncover drivers of endothelial monolayer invasion. We identified keratin-associated protein 5-5 (Krtap5-5) as a candidate. Krtap5...

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Bibliografiska uppgifter
I publikationen:Oncogene
Huvudupphovsmän: Berens, Eric B., Sharif, Ghada M., Schmidt, Marcel O., Yan, Gai, Shuptrine, Casey W., Weiner, Louis M., Glasgow, Eric, Riegel, Anna T., Wellstein, Anton
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2016
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5215748/
https://ncbi.nlm.nih.gov/pubmed/27375028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2016.234
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