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Effects of baseline abdominal pain and bloating on response to lubiprostone in patients with irritable bowel syndrome with constipation

BACKGROUND: Lubiprostone (8 μg b.d.) received US Food and Drug Administration (FDA) approval in 2008 for the treatment of constipation‐predominant irritable bowel syndrome (IBS‐C) in women aged ≥18 years. In 2012, the FDA issued new guidance for IBS‐C clinical trials, recommending a composite endpoi...

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Bibliografski detalji
Izdano u:Aliment Pharmacol Ther
Glavni autori: Chang, L., Chey, W. D., Drossman, D., Losch‐Beridon, T., Wang, M., Lichtlen, P., Mareya, S.
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5215520/
https://ncbi.nlm.nih.gov/pubmed/27669680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/apt.13807
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