The Paradoxical Effects of Different Hepatitis C Viral Loads on Host DNA Damage and Repair Abilities

Hepatitis C virus (HCV)-induced hepatic stress is associated with increased oxidative DNA damage and has been implicated in hepatic inflammation. However, HCV infection and replication are uneven and vary among individual hepatocytes. To investigate the effect of the viral load on host DNA damage, w...

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Vydáno v:PLoS One
Hlavní autoři: Wang, Shu-Chi, Lai, Kuan-Ru, Li, Chia-Yang, Chiang, Chi-Shiun, Yu, Guann-Yi, Sakamoto, Naoya, Tu, Wen-Yu, Hsieh, Meng-Hsuan, Huang, Jee-Fu, Chuang, Wan-Long, Dai, Chia-Yen, Yu, Ming-Lung
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2017
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5215444/
https://ncbi.nlm.nih.gov/pubmed/28052067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0164281
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