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Structure of a Human Astrovirus Capsid-Antibody Complex and Mechanistic Insights into Virus Neutralization

Human astroviruses (HAstVs) are a leading cause of viral diarrhea in young children, the immunocompromised, and the elderly. There are no vaccines or antiviral therapies against HAstV disease. Several lines of evidence point to the presence of protective antibodies in healthy adults as a mechanism g...

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Detalles Bibliográficos
Publicado en:J Virol
Main Authors: Bogdanoff, Walter A., Campos, Jocelyn, Perez, Edmundo I., Yin, Lu, Alexander, David L., DuBois, Rebecca M.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5215351/
https://ncbi.nlm.nih.gov/pubmed/27807234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01859-16
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