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Fine-tuning of Notch signaling sets the boundary of the organ of Corti and establishes sensory cell fates

The signals that induce the organ of Corti and define its boundaries in the cochlea are poorly understood. We show that two Notch modifiers, Lfng and Mfng, are transiently expressed precisely at the neural boundary of the organ of Corti. Cre-Lox fate mapping shows this region gives rise to inner hai...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:eLife
मुख्य लेखकों: Basch, Martin L, Brown, Rogers M, Jen, Hsin-I, Semerci, Fatih, Depreux, Frederic, Edlund, Renée K, Zhang, Hongyuan, Norton, Christine R, Gridley, Thomas, Cole, Susan E, Doetzlhofer, Angelika, Maletic-Savatic, Mirjana, Segil, Neil, Groves, Andrew K
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: eLife Sciences Publications, Ltd 2016
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5215100/
https://ncbi.nlm.nih.gov/pubmed/27966429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.19921
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