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Impact of the mode of protraction of basal insulin therapies on their pharmacokinetic and pharmacodynamic properties and resulting clinical outcomes

Manufacturers of insulin products for diabetes therapy have long sought ways to modify the absorption rate of exogenously administered insulins in an effort to better reproduce the naturally occurring pharmacokinetics of endogenous insulin secretion. Several mechanisms of protraction have been used...

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Bibliographic Details
Published in:Diabetes Obes Metab
Main Authors: Heise, Tim, Mathieu, Chantal
Format: Artigo
Language:Inglês
Published: Blackwell Publishing Ltd 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5215074/
https://ncbi.nlm.nih.gov/pubmed/27593206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/dom.12782
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