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CD4(+)CD25(hi)CD127(−) Treg and CD4(+)CD45R0(+)CD49b(+)LAG3(+) Tr1 cells in bone marrow and peripheral blood samples from children with neuroblastoma

Metastatic spread in the bone marrow (BM) at diagnosis is the worst prognostic factor for neuroblastoma (NB) patients. Here, we analyzed the presence of two immunosuppressive cell subsets, CD4(+)CD25(hi)CD127(−) regulatory T (Treg) cells and CD4(+)CD45R0(+)CD49b(+)LAG3(+) type 1 regulatory (Tr1) cel...

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Detalhes bibliográficos
Publicado no:Oncoimmunology
Main Authors: Morandi, Fabio, Pozzi, Sarah, Barco, Sebastiano, Cangemi, Giuliana, Amoroso, Loredana, Carlini, Barbara, Pistoia, Vito, Corrias, Maria Valeria
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5214984/
https://ncbi.nlm.nih.gov/pubmed/28123887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2016.1249553
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