Repetitive Dosing of Fumed Silica Leads to Pro-Fibrogenic Effects Through Unique Structure-Activity Relationships and Biopersistence in the Lung

Contrary to the notion that the use of fumed silica in consumer products can “generally (be) regarded as safe” (GRAS), the high surface reactivity of pyrogenic silica differs from other forms of synthetic amorphous silica (SAS), including the capacity to induce acute membrane damage and acute pro-in...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:ACS Nano
Prif Awduron: Sun, Bingbing, Wang, Xiang, Liao, Yu-Pei, Ji, Zhaoxia, Chang, Chong Hyun, Pokhrel, Suman, Ku, Justine, Liu, Xiangsheng, Wang, Meiying, Dunphy, Darren R., Li, Ruibin, Meng, Huan, Mädler, Lutz, Brinker, C. Jeffrey, Nel, André E., Xia, Tian
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2016
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5214959/
https://ncbi.nlm.nih.gov/pubmed/27483033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsnano.6b04143
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