Repetitive Dosing of Fumed Silica Leads to Pro-Fibrogenic Effects Through Unique Structure-Activity Relationships and Biopersistence in the Lung

Contrary to the notion that the use of fumed silica in consumer products can “generally (be) regarded as safe” (GRAS), the high surface reactivity of pyrogenic silica differs from other forms of synthetic amorphous silica (SAS), including the capacity to induce acute membrane damage and acute pro-in...

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Udgivet i:ACS Nano
Main Authors: Sun, Bingbing, Wang, Xiang, Liao, Yu-Pei, Ji, Zhaoxia, Chang, Chong Hyun, Pokhrel, Suman, Ku, Justine, Liu, Xiangsheng, Wang, Meiying, Dunphy, Darren R., Li, Ruibin, Meng, Huan, Mädler, Lutz, Brinker, C. Jeffrey, Nel, André E., Xia, Tian
Format: Artigo
Sprog:Inglês
Udgivet: 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5214959/
https://ncbi.nlm.nih.gov/pubmed/27483033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsnano.6b04143
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