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Development of Reverse Transcription Loop-Mediated Isothermal Amplification for Simple and Rapid Detection of Promyelocytic Leukemia–Retinoic Acid Receptor α mRNA

BACKGROUND: Acute promyelocytic leukemia (APL) is a disease characterized by expression of Promyelocytic Leukemia–Retinoic Acid Receptor α (PML-RARα) chimeric mRNA. Although APL is curable, early death due to hemorrhage is a major problem. Here, we report the development of a simple and rapid diagno...

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Detalhes bibliográficos
Publicado no:Yonago Acta Med
Main Authors: Hashimoto, Yuki, Hatayama, Yuki, Kojima, Nao, Morishita, Shota, Matsumoto, Satoko, Hosoda, Yuzuru, Hara, Ayako, Motokura, Toru
Formato: Artigo
Idioma:Inglês
Publicado em: Tottori University Faculty of Medicine 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5214692/
https://ncbi.nlm.nih.gov/pubmed/28070163
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