Phosphorylation of poly(rC) binding protein 1 (PCBP1) contributes to stabilization of mu opioid receptor (MOR) mRNA via interaction with AU-rich element RNA-binding protein 1 (AUF1) and poly A binding protein (PABP)

Gene regulation at the post-transcriptional level is frequently based on cis- and trans-acting factors on target mRNAs. We found a C-rich element (CRE) in mu-opioid receptor (MOR) 3′-untranslated region (UTR) to which poly (rC) binding protein 1 (PCBP1) binds, resulting in MOR mRNA stabilization. RN...

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Publicado no:Gene
Main Authors: Hwang, Cheol Kyu, Wagley, Yadav, Law, Ping-Yee, Wei, Li-Na, Loh, Horace H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5214663/
https://ncbi.nlm.nih.gov/pubmed/27836661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gene.2016.11.003
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