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pH-Dependent Cellular Internalization of Paramagnetic Nanoparticle

A hallmark of the tumor microenvironment in malignant tumor is extracellular acidosis, which can be exploited for targeted delivery of drugs and imaging agents. A pH sensitive paramagnetic nanoaparticle (NP) is developed by incorporating GdDOTA-4AmP MRI contrast agent and pHLIP (pH Low Insertion Pep...

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Détails bibliographiques
Publié dans:ACS Sens
Auteurs principaux: Janic, Branislava, Bhuiyan, Mohammed PI., Ewing, James R., Ali, Meser M.
Format: Artigo
Langue:Inglês
Publié: 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5214587/
https://ncbi.nlm.nih.gov/pubmed/28066811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acssensors.6b00396
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