Ameloblastin induces tumor suppressive phenotype and enhances chemosensitivity to doxorubicin via Src-Stat3 inactivation in osteosarcoma

Ameloblastin (AMBN), the most abundant non-amelogenin enamel matrix protein, plays a role in ameloblast differentiation. Previously, we found that AMBN promoted osteogenic differentiation via the interaction between CD63 and integrin β1, leading to the inactivation of Src; however, how AMBN affects...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Sci Rep
Päätekijät: Ando, Toshinori, Kudo, Yasusei, Iizuka, Shinji, Tsunematsu, Takaaki, Umehara, Hanako, Shrestha, Madhu, Matsuo, Toshihiro, Kubo, Tadahiko, Shimose, Shouji, Arihiro, Koji, Ogawa, Ikuko, Ochi, Mitsuo, Takata, Takashi
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group 2017
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5214574/
https://ncbi.nlm.nih.gov/pubmed/28054649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep40187
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