A patient-derived-xenograft platform to study BRCA-deficient ovarian cancers

Approximately 50% of high-grade serous ovarian cancers (HGSOCs) have defects in genes involved in homologous recombination (HR) (i.e., BRCA1/2). Preclinical models to optimize therapeutic strategies for HR-deficient (HRD) HGSOC are lacking. We developed a preclinical platform for HRD HGSOCs that inc...

全面介紹

Na minha lista:
書目詳細資料
發表在:JCI Insight
Main Authors: George, Erin, Kim, Hyoung, Krepler, Clemens, Wenz, Brandon, Makvandi, Mehran, Tanyi, Janos L., Brown, Eric, Zhang, Rugang, Brafford, Patricia, Jean, Stephanie, Mach, Robert H., Lu, Yiling, Mills, Gordon B., Herlyn, Meenhard, Morgan, Mark, Zhang, Xiaochen, Soslow, Robert, Drapkin, Ronny, Johnson, Neil, Zheng, Ying, Cotsarelis, George, Nathanson, Katherine L., Simpkins, Fiona
格式: Artigo
語言:Inglês
出版: American Society for Clinical Investigation 2017
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5214535/
https://ncbi.nlm.nih.gov/pubmed/28097235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.89760
標簽: 添加標簽
沒有標簽, 成為第一個標記此記錄!

相似書籍