Common Variable Immunodeficiency patients with a phenotypic profile of immunosenescence present with thrombocytopenia

Common variable immunodeficiency (CVID) is a heterogeneous group of diseases. Our aim was to define sub-groups of CVID patients with similar phenotypes and clinical characteristics. Using eight-color flow cytometry, we analyzed both B- and T-cell phenotypes in a cohort of 88 CVID patients and 48 hea...

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Pubblicato in:Sci Rep
Autori principali: Stuchlý, Jan, Kanderová, Veronika, Vlková, Marcela, Heřmanová, Ivana, Slámová, Lucie, Pelák, Ondřej, Taraldsrud, Eli, Jílek, Dalibor, Králíčková, Pavlína, Fevang, Børre, Trková, Marie, Hrušák, Ondřej, Froňková, Eva, Šedivá, Anna, Litzman, Jiří, Kalina, Tomáš
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5214528/
https://ncbi.nlm.nih.gov/pubmed/28054583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep39710
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