Role of N-linked oligosaccharide recognition, glucose trimming, and calnexin in glycoprotein folding and quality control.

Using a pulse-chase approach combined with immunoprecipitation, we showed that newly synthesized influenza virus hemagglutinin (HA) and vesicular stomatitis virus G protein associate transiently during their folding with calnexin, a membrane-bound endoplasmic reticulum (ER) chaperone. Inhibitors of...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Hammond, C, Braakman, I, Helenius, A
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 1994
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC521423/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8302866/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.3.913
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