AMP-Activated Protein Kinase α2 in Neutrophils Regulates Vascular Repair via Hypoxia-Inducible Factor-1α and a Network of Proteins Affecting Metabolism and Apoptosis

RATIONALE: The AMP-activated protein kinase (AMPK) is stimulated by hypoxia, and although the AMPKα1 catalytic subunit has been implicated in angiogenesis, little is known about the role played by the AMPKα2 subunit in vascular repair. OBJECTIVE: To determine the role of the AMPKα2 subunit in vascul...

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Vydáno v:Circ Res
Hlavní autoři: Abdel Malik, Randa, Zippel, Nina, Frömel, Timo, Heidler, Juliana, Zukunft, Sven, Walzog, Barbara, Ansari, Nariman, Pampaloni, Francesco, Wingert, Susanne, Rieger, Michael A., Wittig, Ilka, Fisslthaler, Beate, Fleming, Ingrid
Médium: Artigo
Jazyk:Inglês
Vydáno: Lippincott Williams & Wilkins 2017
Témata:
Cellular Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5213742/
https://ncbi.nlm.nih.gov/pubmed/27777247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.116.309937
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