Nkx2‐5 Is Expressed in Atherosclerotic Plaques and Attenuates Development of Atherosclerosis in Apolipoprotein E–Deficient Mice

BACKGROUND: NK2 homeobox 5 (Nkx2‐5) is a cardiac homeobox transcription factor that is expressed in a broad range of cardiac sublineages. Embryos lacking Nkx2‐5 are nonviable attributed to growth retardation and gross abnormalities of the heart. However, the role of Nkx2‐5 in atherosclerosis remains...

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Dettagli Bibliografici
Pubblicato in:J Am Heart Assoc
Autori principali: Du, Meng, Wang, Xiaojing, Tan, Xin, Li, Xiangrao, Huang, Dandan, Huang, Kun, Yang, Liu, Zhang, Fengxiao, Wang, Yan, Huang, Dan, Huang, Kai
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2016
Soggetti:
Original Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5210424/
https://ncbi.nlm.nih.gov/pubmed/27993833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.116.004440
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