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An accurate, simple prognostic model consisting of age, JAK2, CALR, and MPL mutation status for patients with primary myelofibrosis

In most patients with primary myelofibrosis, one of three mutually exclusive somatic mutations is detected. In approximately 60% of patients, the Janus kinase 2 gene is mutated, in 20%, the calreticulin gene is mutated, and in 5%, the myeloproliferative leukemia virus gene is mutated. Although patie...

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Detalhes bibliográficos
Publicado no:Haematologica
Main Authors: Rozovski, Uri, Verstovsek, Srdan, Manshouri, Taghi, Dembitz, Vilma, Bozinovic, Ksenija, Newberry, Kate, Zhang, Ying, Bove, Joseph E., Pierce, Sherry, Kantarjian, Hagop, Estrov, Zeev
Formato: Artigo
Idioma:Inglês
Publicado em: Ferrata Storti Foundation 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5210235/
https://ncbi.nlm.nih.gov/pubmed/27686378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2016.149765
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