Serotonin improves glucose metabolism by Serotonylation of the small GTPase Rab4 in L6 skeletal muscle cells

BACKGROUND: Serotonin (5-HT) improves insulin sensitivity and glucose metabolism, however, the underlying molecular mechanism has remained elusive. Previous studies suggest that 5-HT can activate intracellular small GTPases directly by covalent binding, a process termed serotonylation. Activated sma...

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Dettagli Bibliografici
Pubblicato in:Diabetol Metab Syndr
Autori principali: Al-Zoairy, Ramona, Pedrini, Michael T., Khan, Mohammad Imran, Engl, Julia, Tschoner, Alexander, Ebenbichler, Christoph, Gstraunthaler, Gerhard, Salzmann, Karin, Bakry, Rania, Niederwanger, Andreas
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2017
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5209910/
https://ncbi.nlm.nih.gov/pubmed/28053672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13098-016-0201-1
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