Placental mitochondrial DNA and CYP1A1 gene methylation as molecular signatures for tobacco smoke exposure in pregnant women and the relevance for birth weight

BACKGROUND: Maternal smoking during pregnancy results in an increased risk of low birth weight through perturbations in the utero-placental exchange. Epigenetics and mitochondrial function in fetal tissues might be molecular signatures responsive to in utero tobacco smoke exposure. METHODS: In the f...

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Detalhes bibliográficos
Publicado no:J Transl Med
Main Authors: Janssen, Bram G., Gyselaers, Wilfried, Byun, Hyang-Min, Roels, Harry A., Cuypers, Ann, Baccarelli, Andrea A., Nawrot, Tim S.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5209876/
https://ncbi.nlm.nih.gov/pubmed/28052772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-016-1113-4
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