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Agouti Related Peptide Secreted Via Human Mesenchymal Stem Cells Upregulates Proteasome Activity in an Alzheimer’s Disease Model

The activity of the ubiquitin proteasome system (UPS) is downregulated in aggregation diseases such as Alzheimer’s disease (AD). In this study, we investigated the therapeutic potential of the Agouti-related peptide (AgRP), which is secreted by human mesenchymal stem cells (MSCs), in terms of its ef...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Lee, Na Kyung, Park, Sang Eon, Kwon, Soo Jin, Shim, Sangmi, Byeon, Yeji, Kim, Jong-Hwa, Na, Duk L., Chang, Jong Wook
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5209736/
https://ncbi.nlm.nih.gov/pubmed/28051110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep39340
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