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Validation of suitable normalizers for miR expression patterns analysis covering tumour heterogeneity

Oncogenic microRNAs (miRs) have emerged as diagnostic biomarkers and novel molecular targets for anti-cancer drug therapies. Real-time quantitative PCR (qPCR) is one of the most powerful techniques for analyzing miRs; however, the use of unsuitable normalizers might bias the results. Tumour heteroge...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Morata-Tarifa, C., Picon-Ruiz, M., Griñan-Lison, C., Boulaiz, H., Perán, M., Garcia, M. A., Marchal, J. A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5209713/
https://ncbi.nlm.nih.gov/pubmed/28051134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep39782
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